Didehydrostemofoline formal synthesis

Stephen Martin and co-workers have reported in ACIE on a formal synthesis of didehydrostemofoline.

ACIE paper

Acetylaranotin synthesis

Sarah Reisman and co-workers have reported in JACS on a synthesis of acetylaranotin.

JACS paper

Ir-catalyzed cascade

Xingwei Li and co-workers at the Chinese Academy of Sciences have reported on the formation of azomethine ylides using nitron alkynes.

ACIEE paper

Olefination with an alkyne

Kurt Gothelf and co-workers from Aarhus University have reported in Organic Letters on a beta-olefination process involving an alkynoate and an aldehyde in the presence of 1,3,5-triaza-7-phospha-adamantane (PTA).

OL paper

Dimethylsulfonium Methylide Cascade

If I were to tell you a dimethylsulfonium methylide were used as the reagent – you’d probably predict it to be a Corey-Chaykovsky reaction.  However, in this case reported by Philip Fuchs and colleague at Purdue, it is an SN2 prime addition followed by an elimination of dimethyl sulfide.

Chem Comm paper

Multi-Component Cascade

Xian Huang and co-workers from Zhejiang University have published in Organic Letters on a multi-component coupling approach that takes advantage of an interesting way to form a phosphorous ylide – by addition of an alkyl lithium onto an alkynyl phosphine oxide.

 

JOC paper

Oxonium Ylide Approach to Seven Membered Rings

F. G. West and co-workers at the University of Alberta have published in Organic Letters on a copper catalyzed oxonium ylide generation.

 

OL paper

1,3-Dipolar Cycloaddition Followed by Decarboxylation

John Ryan and co-workers at the University of Melbourne have published in Organic Letters on a reaction which involves the 1,3-dipolar cycloaddition between an anhydride and a non-stabilized ylide followed by decarboxylation.

 

OL paper

Rhodium catalyzed Oxonium Ylide

Stephen Clark and co-workers from the University of Glasgow have reported in ACIEE on their syntheses of cladiellins using an oxonium ylide approach via a rhodium dimer catalyst.

 

ACIEE paper

Epoxide and Oxetane Expansions

Andrey Fokin and co-workers at Justus-Liebig University have published in the Journal of Organic Chemistry on a method to expand epoxides using a sulfur ylide.

JOC paper