Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for the ‘Shapiro’ Category

Tosyl hydrazones to substituted alkenes

Posted by naturalproductman on April 17, 2012

William Kerr and co-workers from the University of Strathclyde have reported in Organic Letters on the conversion of tosyl hydrazones to substituted alkenes.  I’ve done a similar reaction converting tosyl hydrazones to a monosubstituted alkene using n-BuLi.

tosyl hydrazone

OL paper

Posted in Cascade Reactions, Methodology, Named Reactions, Shapiro | Leave a Comment »