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Archive for the ‘Vanadium’ Category

Coupling between boron and silyl enolates (not a Mukaiyama-Michael)

Posted by naturalproductman on August 6, 2015

At first glance, I thought it was a Mukaiyama-Michael reaction with the silyl enol ether to form a dicarbonyl product, but then you look carefully and see that the product is a 1,4-dicarbonyl (not 1,5-dicarbonyl) and the other reactant is a boron enolate.

JACS paper

Posted in Methodology, Transition Metal, Vanadium | Leave a Comment »

Dual catalysis

Posted by naturalproductman on July 26, 2011

Barry Trost and co-workers have reported in JACS on a dual catalysis reaction using a vanadium allenoate and a palladium pi allyl unit to form alpha,beta-unsaturated ketones.


JACS paper

Posted in Dual Catalysis, Methodology, Named Reactions, Palladium, Transition Metal, Vanadium | Leave a Comment »

Dual Catalysis

Posted by naturalproductman on January 25, 2011

Barry Trost and co-worker have published in JACS on a reaction involving dual catalysis. That is, a palladium catalyst and a vanadium catalyst independently reacting with two separate substrates then the two intermediate metal species join to make the product.  In this case, the palladium catalyst makes a pi-allyl intermediate from an allylic carbonate and the vanadium catalyst rearranges a propargylic alcohol to form an allenoxy vanadium intermediate.

dual catalysis

JACS paper

Posted in Cascade Reactions, Dual Catalysis, Methodology, Palladium, Transition Metal, Vanadium | Leave a Comment »


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