Naturalproductman’s Blog

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Archive for the ‘Organocatalytic’ Category

Pyridinium catalyzed glycosylation

Posted by naturalproductman on July 17, 2015

Albrecht Berkessel and co-workers at Cologne University have reported in ACIE on a pyridinium catalyzed glycosylation reaction.
pyridinium
ACIE paper

Posted in Cascade Reactions, Methodology, Organocatalytic | Leave a Comment »

Nazarov-semipinacol cascade

Posted by naturalproductman on July 11, 2015

Take a cyclobutanol bearing dienone and see what kind of Nazarov reaction occurs…Yong-Qiang Tu and co-workers at Lanzhou University reported in JACS on this interesting asymmetric transformation.

Nazarov

JACS paper

Posted in Asymmetric, Cascade Reactions, Methodology, Named Reactions, Nazarov cyclization, Organocatalytic | Leave a Comment »

Stereospecific reaction with D2O but not with H2O

Posted by naturalproductman on July 10, 2015

Jik Choon and co-workers at the University of Toronto have reported in ACIE on an interesting sttereoinversion that occurs in D2O but not in H2O.

asymmetric

ACIE paper

Posted in Asymmetric, Methodology, Organocatalytic | Leave a Comment »

From carbenoids to allenoates

Posted by naturalproductman on July 1, 2015

Xiaoming Feng and co-workers from Sichuan University have reported in the transformation of terminal alkynes to allenoates using diazo acetates.

diazo

ACIE paper

Posted in Carbene, Methodology, Organocatalytic | Leave a Comment »

Binaphthylamine catalyzed Michael addition

Posted by naturalproductman on July 1, 2015

When I saw that binaphthylamine on the abstract, I immediately thought of Keiji Maruoka and it was his work.

arylamine

ACIE paper

Posted in Methodology, Michael, Named Reactions, Organocatalytic | Leave a Comment »

Cyclic 1,3-carbonates from carbon dioxide fixation

Posted by naturalproductman on June 7, 2015

Jeffrey Johnston and co-workers have reported in JACS on the synthesis of 1,3-cyclic carbonates from butenol, carbon dioxide and NIS.
carbonate
JACS paper

Posted in Asymmetric, Methodology, Organocatalytic | Leave a Comment »

A3 reaction with thiourea cocatalyst

Posted by naturalproductman on April 12, 2015

Daniel Seidel and co-worker at Rutgers have reported in JACS on an asymmetric A3 reaction using a thiourea cocatalyst.

A3

JACS paper

Posted in Cascade Reactions, Copper, Methodology, Multi-Component Coupling, Organocatalytic, Transition Metal | Leave a Comment »

Phosphoric acid catalyzed alpha-amination

Posted by naturalproductman on March 5, 2015

Dean Toste and colleague have reported in JACS on a phosphoric acid catalyzed alpha-amination of ketones – I am reminded of Hisashi Yamamoto’s silver BINAP methodology back in 2003.

phosphoric acid

JACS paper

Posted in Asymmetric, Methodology, Organocatalytic | Leave a Comment »

Organocatalytic epoxidation

Posted by naturalproductman on August 31, 2014

Philip Bulman Page and co-workers at the University of East Anglia have reported in Tetrahedron on an iminium catalyzed epoxidation.
epoxidation

Tetrahedron paper

Posted in Asymmetric, Methodology, Organocatalytic | Leave a Comment »

Bislactone desymmetrization

Posted by naturalproductman on July 27, 2014

Jieping Zhu and co-workers have reported in ACIE on the synthesis of rhazinilam and leucomidine B.

desymmetrize

ACIE paper

Posted in Alkaloids, Asymmetric, C2-Symmetric, Cascade Reactions, Methodology, Organocatalytic | Leave a Comment »

 
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