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Archive for the ‘Cascade Reactions’ Category

multiple reactions back to back (to back) in one go

Ni-catalyzed cyclopropanation

Posted by naturalproductman on July 30, 2015

Peter Chen and co-workers from ETH Zurich have reported in ACIE on a nickel catalyzed cyclopropanation. Looks similar to a Corey-Chaykovsky cyclopropanation because of the formation of an ylide.

nickel

ACIE paper

Posted in Carbene, Cascade Reactions, Methodology, Nickel, Transition Metal | Leave a Comment »

Hydroamidocarbonylation

Posted by naturalproductman on July 30, 2015

Matthias Keller and co-workers have reported in ACIE on a hydroamidocarbonylation of olefins.
hydroamidocarbonylation

ACIE paper

Posted in Cascade Reactions, Methodology, Palladium, Transition Metal | Leave a Comment »

Cannizzaro cascade

Posted by naturalproductman on July 30, 2015

Simon Woodward and co-workers have reported in ACIE on a Cannizzaro cascade reaction using tert-butyl lithium.
cascade
ACIE paper

Posted in Cascade Reactions, Methodology, Multi-Component Coupling | Leave a Comment »

4pi-Electrocyclic ring opening cascade

Posted by naturalproductman on July 23, 2015

Kiyosei Takasu and co-workers from Kyoto University have reported in JACS on a ring expansion cross coupling cascade.

JACS paper

Posted in Cascade Reactions, Electrocyclization, Methodology, Palladium, Transition Metal | Leave a Comment »

Hosieine A synthesis

Posted by naturalproductman on July 22, 2015

Ran Hong and co-workers at SIOC have reported in ACIE on the synthesis of hosieine A. The pyridone moiety reminds of lyconadin.

alkaloid

ACIE paper

Posted in Alkaloids, Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

Blue-LED induced cascade

Posted by naturalproductman on July 17, 2015

Zhiyong Jiang and co-workers from Henan University have reported in ACIE on a radical cascade cyclization using blue light emitted diodes.

radical

ACIE paper

Posted in Cascade Reactions, Light Mediated, Methodology, Radical Chemistry | Leave a Comment »

Pyridinium catalyzed glycosylation

Posted by naturalproductman on July 17, 2015

Albrecht Berkessel and co-workers at Cologne University have reported in ACIE on a pyridinium catalyzed glycosylation reaction.
pyridinium
ACIE paper

Posted in Cascade Reactions, Methodology, Organocatalytic | Leave a Comment »

C-C bond cleavage of alpha-aryl acetals

Posted by naturalproductman on July 13, 2015

Thomas Lectka and co-workers from Johns Hopkins University have reported in Chemical Science on an interesting C-C bond cleavage process.

C-C

Chemical Science paper

Posted in C-C Bond Breaking, Cascade Reactions, Light Mediated, Methodology | Leave a Comment »

On the utility of allenoates

Posted by naturalproductman on July 13, 2015

Hongchao Guo and co-workers from China Agricultural University have reported in Chemical Communications on a [4+1] cyclization of allenoates with anilines to form substituted indolines.

4+1

Chem Comm paper

Posted in Allenes, Cascade Reactions, Methodology | Leave a Comment »

Newman-Kwart reaction mechanism

Posted by naturalproductman on July 13, 2015

Hafize Ozcan and co-workers from Trakya University in Turkey have reported in Tetrahedron on an interesting mechanistic investigation of the Newman-Kwart reaction.

Newman-Kwart

Tetrahedron paper

Posted in Cascade Reactions, Computational, DFT, Electrocyclization, Mechanistic, Methodology, Named Reactions, Newman-Kwart, Sigmatropic Rearrangements | Leave a Comment »

 
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