Naturalproductman’s Blog

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Archive for the ‘Crystal Structure’ Category

Posted by naturalproductman on March 28, 2014

Hideko Koshima and co-workers from Ehime University have reported in JOC on an asymmetric photocyclization of crystals to form chiral cyclobutenols using a chiral counterion.

photocyclization

JOC paper

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Posted in Asymmetric, Crystal Structure, Methodology | Leave a Comment »

Peloruside vs. Taxol

Posted by naturalproductman on January 30, 2014

Michel Steinmetz and co-workers from Paul Scherrer Institut in Switzerland have reported in ACIE on a crystal structure of peloruside bound to beta-tubulin. Interestingly, peloruside and taxol bind to beta-tubulin differently.

taxol

ACIE paper

Posted in Cancer, Crystal Structure, Polyketides | Leave a Comment »