Naturalproductman’s Blog

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Archive for the ‘Isotope effects’ Category


Posted by naturalproductman on May 14, 2014

Cristina de Meo and co-workers from Southern Illinois University reported in Organic Letters on a thiosialoside elimination of a thiophenol group, occuring by syn-elimination.


OL paper

Posted in Half-chair, Isotope effects, Mechanistic | 1 Comment »

Half chair transition state

Posted by naturalproductman on February 17, 2012

Andrew Bennet and co-workers from Simon Fraser University have reported in JACS on a transition state study of a sialidase enzyme.


JACS paper

Posted in Enzymes, Glucoside, Isotope effects, Mechanistic, Methodology, Proteins | Leave a Comment »

Ru-catalyzed hydroamidation

Posted by naturalproductman on April 26, 2011

Lukas Goossen and co-workers at TU Kaiserslautern have reported in JACS on a mechanistic investigation of a ruthenium catalyzed hydroamidation reaction of an alkyne.


JACS paper

Posted in Cascade Reactions, Isotope effects, Mechanistic, Methodology, Ruthenium, Transition Metal | Leave a Comment »


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