Amine/Palladium dual catalysis

Sanzhong Luo and co-workers from the Chinese Academy of Sciences have reported in ACIE on a dual catalysis approach to alkylate beta-keto carbonyls with allylic alcohols.

ACIE paper

Pd pi-allyl

Shu-Li You and co-workers at SIOC have reported in JACS on some mechanistic studies of a Pd pi-allyl chemistry.

JACS paper

Kendomycin synthesis

Hirokazu Arimoto and co-workers from Tohoku University have reported in ACIE on the synthesis of kendomycin.

ACIE paper

Allylation

David Lupton and colleague from Monash University have reported in ACIE on a Tsuji-Trost approach for the synthesis of (−)-Kopsihainanine A.

ACIE paper

Asymmetric palladium cascade

Hiroaki Sasai and co-workers from Osaka University have reported in Organic Letters on a palladium catalyzed transformation of a carboxylic acid tethered with an alkene to a lactone.

OL paper

Quaternary carbon center via pi allyl

James Morken and co-workers at Boston College have reported in JACS on a palladium catalyzed coupling between allyl carbonates and allyl boronates.

JACS paper

Kainic acid from a vinyl aziridine

Varinder Aggarwal and co-workers from the University of Bristol have reported in ACIEE on a [3+2] reaction between a vinyl aziridine and a Michael acceptor while taking advantage of Tsuji-Trost allylation.  Additionally, they cleaved off the phenyl group on the resulting pyrrolidine ring using a RuCl3/H5IO6/NaIO4 oxidation protocol.

ACIEE paper

Intermolecular Oxy-Michael Followed by Tsuji-Trost

Dirk Menche and co-workers at the University of Heidelberg have published in ACIEE on an intermolecular oxy-Michael addition of an alcohol onto a nitro-olefin followed by a Tsuji-Trost reaction to form a tetrahydropyran.

ACIEE paper

Spirocyclization of an Allylic Carbonate

Yasumasa Hamada and co-workers from Chiba University have published in Organic Letters on a palladium catalyzed spirocyclization of a phenol tethered by a allylic carbonate.

 

OL paper

Decarboxylative Asymmetric Allylic Alkylation

Barry Trost and co-workers have published in JACS on a palladium catalyzed decarboxylative asymmetric allylic alkylation (DAAA) reaction as an alternative to an enolate alkylation.

JACS paper