Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for the ‘Diseases’ Category

Lactate dehydrogenase inhibitors for epilepsy

Posted by naturalproductman on March 21, 2015

Tsuyoshi Inoue and co-workers at Okayama University have reported in Science on lactate dehydrogenase inhibition using stiripentol analogs as a strategy to treat epileptic seizures.

Science paper

Posted in Diseases | Leave a Comment »

Efavirenz flow synthesis

Posted by naturalproductman on March 5, 2015

Peter Seeberger and co-workers at Max Planck Institute of Colloids and Interfaces have reported in ACIE on the flow synthesis of efavirenz.

flow

ACIE paper

Posted in Flow, HIV, New Setups, Total Synthesis | Leave a Comment »

Salinipostins

Posted by naturalproductman on January 18, 2015

Roger Linington and co-workers from UCSC have reported in JOC on the isolation of salinipostins.

salinipostins
JOC paper

Posted in Diseases, Malaria, Phosphates | Leave a Comment »

Myrioneurinol synthesis

Posted by naturalproductman on November 4, 2014

Steven Weinreb and colleague at Penn State have reported in ACIE on the synthesis of myrioneurinol.

alkaloid

ACIE paper

Posted in Diseases, Malaria, Total Synthesis | Leave a Comment »

ZMapp vs. ebola

Posted by naturalproductman on August 30, 2014

Gary Kopinger and co-workers from the University of Manitoba have reported in Nature on ZMapp’s reversion of the ebola virus.
Nature paper

Posted in Anti-viral, Diseases | Leave a Comment »

Aspergillomarasmine A

Posted by naturalproductman on June 28, 2014

Gerald Wright and co-workers from McMaster University in Canada have reported in Nature on aspergillomarasmine A being a good inhibitor for the New Dehli Metallo beta-lactamase 1 (NDM-1) enzyme.

 

Nature paper

Posted in Amino Acids, Antibiotics, Diseases | 1 Comment »

Anti-malarial pyrrolopyrazines

Posted by naturalproductman on June 7, 2014

Gisbert Schneider and co-workers from ETH Zurich have reported in ACIE on some anti-malarial pyrrolopyrazines.

ACIE paper

Posted in Diseases, Malaria, Unnatural Products | Leave a Comment »

Zoaramine

Posted by naturalproductman on June 3, 2014

Antonio Hernandez Daranas and co-workers at University La Laguna in Spain have reported in Organic Letters on the isolation of zoaramine.
zoaramine

OL paper

Posted in Alkaloids, Osteoporosis | Leave a Comment »

Logeracemin A

Posted by naturalproductman on May 21, 2014

Jian-Min Yue and co-workers from the Chinese Academy of Sciences have reported in JACS on the isolation of logeracemin A.

logeracemin A

JACS paper

Posted in Alkaloids, C2-Symmetric, Diseases, HIV | Leave a Comment »

Cardamom peroxide synthesis

Posted by naturalproductman on March 27, 2014

Thomas Maimone and co-worker from UC Berkeley have reported in JACS on a 4-step synthesis of cardamom peroxide from myrtenal.

 

 

JACS paper

Posted in Diseases, Malaria, Peroxides, Total Synthesis | Leave a Comment »

 
Follow

Get every new post delivered to your Inbox.

Join 77 other followers