HIV integrase inhibitor synthesis

Chris Senanayake and co-workers from Boehringer-Ingelheim have reported in ACIE on the synthesis of

ACIE paper

MAP4K4 for neurodegenerative diseases

Herbert Waldmann and co-workers at Technische Universität Dortmund have reported in ACIE on MAP4K4 as a target for neurodegenerative diseases.

ACIE paper

Kalihinol B synthesis

Christopher Vanderwal and co-workers have reported in JACS on the synthesis of kalihinol B.

JACS paper

Lactate dehydrogenase inhibitors for epilepsy

Tsuyoshi Inoue and co-workers at Okayama University have reported in Science on lactate dehydrogenase inhibition using stiripentol analogs as a strategy to treat epileptic seizures.

Science paper

Efavirenz flow synthesis

Peter Seeberger and co-workers at Max Planck Institute of Colloids and Interfaces have reported in ACIE on the flow synthesis of efavirenz.

ACIE paper

Salinipostins

Roger Linington and co-workers from UCSC have reported in JOC on the isolation of salinipostins.

JOC paper

Myrioneurinol synthesis

Steven Weinreb and colleague at Penn State have reported in ACIE on the synthesis of myrioneurinol.

ACIE paper

ZMapp vs. ebola

Gary Kopinger and co-workers from the University of Manitoba have reported in Nature on ZMapp’s reversion of the ebola virus.
Nature paper

Aspergillomarasmine A

Gerald Wright and co-workers from McMaster University in Canada have reported in Nature on aspergillomarasmine A being a good inhibitor for the New Dehli Metallo beta-lactamase 1 (NDM-1) enzyme.

 

Nature paper

Anti-malarial pyrrolopyrazines

Gisbert Schneider and co-workers from ETH Zurich have reported in ACIE on some anti-malarial pyrrolopyrazines.

ACIE paper