Fischer Carbene-Dienophile Reaction

Binay Krishna Ghorai and co-worker at Bengal Engineering and Science University have published in the Beilstein Journal of Organic Chemistry on a multicomponent reaction involving a Fischer carbene addition to a pyrazinyl ketone followed by a Diels-Alder reaction.

Beilstein JOC paper

Hetero-Diels-Alder

Janusz Jurczak and co-workers at Polish Academy of Sciences have published in Synlett on a hetero-Diels-Alder reaction by using a chromium-Schiff base complex.

Synlett paper

NHK Reaction

Thomas Horstmann and co-workers from Eisai have recently reported in Tetrahedron on an alternative to make Baylis-Hillman adducts using the Nozaki-Hiyama-Kishi coupling protocol.  The starting material is of course the usual aldehyde from the NHK reaction but also an alpha-bromo-enone.

TL paper

Kendomycin Synthesis

Masaya Nakata and co-workers at Keio University have recently published in Organic Letters on an approach for kendomycin.  The key reaction was a macrocyclization of a chromium carbene complex with an alkyne, also known as the Dotz benzannulation.

OL paper