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Intramolecular Oxy-Michael

Posted by naturalproductman on October 29, 2009

Jayanta Ray and co-workers at IIT Kharagpur have recently published in Tetrahedron Letters on synthesis of polycyclic furans and tetrahydrofurans via an intramolecular oxy-Michael addition using either a reductant or a base to effect the transformation. I think I’ve seen similar substrates but they underwent a hetero-Diels-Alder reaction.

not a diels alder

Tetrahedron Letters paper

This entry was posted on October 29, 2009 at 8:25 am and is filed under Conjugate Additions, Methodology, Ring forming. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

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