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Ophiobolin synthesis

Posted by naturalproductman on September 15, 2011

Masahisa Nakada and co-workers have reported in ACIEE on a synthesis of ophiobolin where the seven membered ring was accessed via a ring closing metathesis.

ophiobolin

ACIEE paper

This entry was posted on September 15, 2011 at 10:52 am and is filed under Cancer, Cascade Reactions, melanoma, Metathesis, Methodology, Named Reactions, Reformatsky, Ring forming, Ruthenium, Sesquiterpenoids, Seven-Membered Rings, Transition Metal. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

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