Robert Grubbs and co-workers have reported in JACS on factors that influence Z-selective olefin metathesis.
Archive for the ‘Metathesis’ Category
Z-selective olefin metathesis
Posted by naturalproductman on August 20, 2014
Posted in Metathesis, Methodology, Ring forming, Ruthenium, Transition Metal | Leave a Comment »
WF-1360F synthesis
Posted by naturalproductman on April 23, 2013
Posted in Macrolides, Metathesis, Methodology, Total Synthesis | Leave a Comment »
Spirangien A synthesis
Posted by naturalproductman on January 17, 2013
Mark Rizzacasa and co-workers from the University of Melbourne have reported in Organic Letters on their formal synthesis of spirangien A.
Posted in Iron, Manganese, Metathesis, Methodology, Polyketides, Spiroketals, Transition Metal | Leave a Comment »
FD-895 synthesis
Posted by naturalproductman on October 25, 2012
Michael Burkart and James J. La Clair and colleagues at UCSD have reported in Org Lett on the synthesis of
Posted in Macrolides, Metathesis, Methodology, Polyketides, Ring forming, Ruthenium, Structural Reassignment, Transition Metal | Leave a Comment »
Enyne metathesis
Posted by naturalproductman on August 6, 2012
Steven Diver and co-workers from the University of Buffalo have reported in Organic Letters on an enyne metathesis reaction.
Posted in Cascade Reactions, Metathesis, Methodology | Leave a Comment »
Englerin A formal synthesis
Posted by naturalproductman on May 7, 2012
Kathlynn Parker and colleague have reported in Organic Letters on a formal synthesis of englerin A.
Posted in Cascade Reactions, Metathesis, Methodology, Ruthenium, Sesquiterpenoids, Transition Metal | Leave a Comment »
Fluorous mixture synthesis application
Posted by naturalproductman on May 1, 2012
Dennis Curran and co-workers at the University of Pittsburgh have applied fluorous mixture synthesis to assign the stereochemistry of a macrolide. Fluorous mixture synthesis is a technique where they install fluorinated tag protecting groups on the alcohols where each tag varies by the number of fluorines. They are able to separate the tagged compounds based on the number of flourines on the tags.
Posted in Macrolides, Metathesis, Methodology, Ruthenium, Total Synthesis, Transition Metal | Leave a Comment »
Oxyingenol synthesis
Posted by naturalproductman on April 17, 2012
Hideo Kigoshi and co-workers from the University of Tsukuba have reported in ACIE on the synthesis of oxyingenol.
Posted in Diseases, Diterpenoids, HIV, Metathesis, Methodology, Ruthenium, Sigmatropic Rearrangements, Total Synthesis, Transition Metal | Leave a Comment »
Viriditoxin
Posted by naturalproductman on January 24, 2012
Jared Shaw and co-workers at UC Davis have reported in Synthesis on their approach towards viriditoxin.
Posted in Aromatic, C2-Symmetric, Dimer, Metathesis, Methodology, Total Synthesis | Leave a Comment »
Enyne cross metathesis
Posted by naturalproductman on December 14, 2011
Seunghoon Shin and co-workers at Hanyang University have reported in JACS on a gold catalyzed enyne cross metathesis between propiolic acids and alkenes.
Posted in Cascade Reactions, Computational, DFT, Gold, Mechanistic, Metathesis, Methodology, Transition Metal | Leave a Comment »