Alotaketals A and B
Posted by naturalproductman on October 30, 2009
Raymond Andersen’s group at the University of British Columbia has recently reported in Organic Letters on the isolation of a novel sesquiterpenoid structure dubbed alotaketal. This compound and its related structure has cAMP activating abilities with EC50 of 18 and 240 nM. The spiroketal structures were isolated from the marine sponge Hamigera.